Lake Shore Drive was the inspiration for the 1980's Activision game "Freeway." Well, the original name was "Bloody Human Freeway" but most of us remember it being marketed with a chicken, not a person, crossing the lanes of traffic.
From Atari Age:
Even though Freeway looks a bit like Frogger at first glance, the two games are actually very different. According to David Crane, he got the idea for Freeway from watching a man trying to cross Lake Shore Drive during rush-hour traffic while attending Chicago's Consumer Electronic Show.
More at Atari Age including a ROM you can download and play the game on your computer.